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📚 Book Reviews

SmartStrongAlive — Annette Thompson

Published under Annette Thompson's byline on SmartStrongAlive. Each review has a Substack/website version and a Goodreads version. Click a book to expand it.
Book 1
Estrogen Matters
Avrum Bluming, MD and Carol Tavris, PhD (2018, updated 2023)

The Book That Made Me Furious on Behalf of Every Woman Who Wasn't Given a Choice

My mother has Alzheimer's. She was never prescribed HRT. Her doctor — like virtually every doctor in America after 2002 — stopped offering it. That was the year the Women's Health Initiative (WHI) released findings that were splashed across every newspaper in the country: hormone replacement therapy causes breast cancer. Causes heart disease. Don't take it.

Except the study was badly designed, applied to the wrong age group, used synthetic progestins instead of bioidentical progesterone, and its statistical conclusions were misrepresented in ways that a second-year epidemiology student could dismantle. But by then, the damage was done. An entire generation of women — including my mother — lost access to a therapy that might have protected their brains.

Estrogen Matters is the book that lays this out in devastating, documented detail. Dr. Avrum Bluming is an oncologist who spent decades prescribing HRT to breast cancer survivors when every other oncologist in the country was too scared to touch it. Not recklessly — carefully, with years of follow-up data on his patients. Carol Tavris is the social psychologist who co-wrote Mistakes Were Made (But Not By Me), which means she is constitutionally incapable of letting motivated reasoning slide. Together they are the most dangerous pair of authors in women's health: one has the clinical data, and the other knows exactly how institutional self-deception works.

What destroyed me about this book was the neuroprotection chapter. The evidence that estrogen has a timing-dependent protective effect on the brain has been building for decades. Start HRT within ten years of menopause, and the risk of Alzheimer's drops meaningfully. Wait until your seventies, and you may have already missed the window. My mother went into menopause in the mid-1990s. She was told, like everyone else, that hormones were dangerous. She stopped. She waited. The window closed.

I don't know if HRT would have saved her memory. Neither does anyone. But I know she was never given the chance to find out — because the medical establishment, burned by bad press and terrified of liability, took that option off the table without a proper accounting of what they were trading away.

If you are perimenopausal or postmenopausal, if you have a family history of Alzheimer's, if you have ever been told HRT is "not worth the risk" without a real conversation about what risk actually means — read this book. Then hand it to your doctor.

Estrogen Matters is not a polemic. It is a meticulously sourced argument. And it made me angrier than any book I have read in years, because the anger is completely warranted.

I started this book as a curious reader. I finished it furious.

My mother has Alzheimer's. She was never given HRT — her doctor, like most doctors after the 2002 WHI study, quietly stopped offering it. This book explains exactly what went wrong with that study, why its conclusions were misrepresented, and what the actual evidence says about estrogen and breast cancer, heart disease, and — the part that broke my heart — brain health.

Dr. Bluming is an oncologist who kept prescribing hormones to breast cancer survivors when everyone else ran scared, and he has the long-term patient data to back his decisions. Carol Tavris is a social psychologist who specializes in how institutions protect themselves from admitting mistakes. Together they dismantle the WHI findings chapter by chapter, citation by citation, without ever losing their humanity.

The neuroprotection chapter nearly undid me. There is a timing window — start estrogen within ten years of menopause and the protective effect on the brain is real and meaningful. Miss it, and you may not get it back. My mother missed it because her doctors took the option away from her.

I don't know if HRT would have changed her story. But I know she deserved the chance to find out.

Read this if you are approaching menopause. Read it if you have a mother who has Alzheimer's. Read it if your doctor has ever said the words "the risks outweigh the benefits" without explaining where those numbers came from.

⭐⭐⭐⭐⭐
Book 2
The New Menopause
Mary Claire Haver, MD (2024)

The Manual We Should Have Been Handed at Our First Hot Flash

Here is what happened to most of us: something went wrong — the sleep, the weight, the mood, the memory, the body that no longer behaved the way it used to — and we went to our doctors. Who ran some tests, found nothing alarming, and suggested perhaps we were stressed. Perhaps we needed to sleep more. Perhaps this was just aging.

Dr. Mary Claire Haver became famous on social media because she was the first OB/GYN most of us had ever seen just... tell the truth. On camera. In plain language. Without the usual hedging and the liability-driven softening of every actual fact. She had a lot of followers before her book came out. After The New Menopause published, she had an army.

I understand why. This book is comprehensive in a way that women's health books almost never are. It covers HRT — the types, the delivery methods, the evidence behind each — in enough detail that you can walk into your doctor's appointment and have an actual conversation instead of nodding along. It covers lifestyle: what exercise does and doesn't do for menopause symptoms (spoiler: cardio alone is not enough, and Dr. Haver is very clear about that). It covers GLP-1s, which no menopause book published even two years earlier would have touched. It covers labs — which ones to ask for, what ranges to look for, why your doctor's "normal" may not be optimal for you.

What I love most about Dr. Haver is that she treats the reader as an adult. She does not present "both sides" of questions that do not actually have two equal sides. She does not soften her assessment of what the WHI did to an entire generation of women. She is warm and funny and clearly motivated by genuine outrage on behalf of her patients — but she never lets the outrage override the evidence.

If you have been symptomatic and dismissed, this book will give you vocabulary, confidence, and a checklist for your next appointment. If you are in the early stages of perimenopause and not yet symptomatic but want to understand what is coming, it is the best orientation to the landscape that currently exists. If you are a woman in your thirties who has not thought about menopause yet: read the perimenopause chapter now. Your future self will thank you.

The New Menopause is the book I send every woman who messages SmartStrongAlive asking where to start. It is that useful.

If I had to pick one book to hand every perimenopausal woman in America, it would be this one.

Dr. Mary Claire Haver became a social media phenomenon because she talked honestly about menopause in a medical landscape that had spent decades hedging, minimizing, and telling women that their symptoms were "just aging." This book is her comprehensive, evidence-based, zero-hedging guide to navigating the whole thing.

She covers HRT types and delivery methods in enough detail that you can have an actual conversation with your doctor instead of a one-sided presentation. She covers lifestyle — and she is honest that cardio alone is not the answer. She covers GLP-1s, labs, sexual health, mental health, bone density, cardiovascular risk, and every symptom category I'd been piecing together from a dozen different sources for years. It's all in one place.

What I appreciate most is that Dr. Haver treats the reader as a peer, not a patient. She is not performing balance on questions where the evidence is actually pretty clear. She is warm and direct and appropriately furious about what the WHI did to women's care — without ever letting the outrage override the science.

I sent this book to three friends within a week of finishing it. I wish it had existed ten years ago.

⭐⭐⭐⭐⭐
Book 3
You Are Not Broken
Kelly Casperson, MD (2022)

The Doctor Who Said the Quiet Part Out Loud

Let me tell you something that medicine has been extremely reluctant to say out loud: women's sexual health in midlife is systematically undertreated, under-researched, and — perhaps most damaging — culturally framed as a problem that is simply supposed to stop mattering at a certain age.

Dr. Kelly Casperson is a urologist. She sees patients. She hears what happens when libido disappears, when sex becomes painful, when women feel like strangers in their own bodies — and she has watched the medical system respond to those complaints with a shrug or an antidepressant. So she wrote a book.

You Are Not Broken is what the title promises: a methodical, evidence-based, deeply compassionate argument that the things happening to your body and your desire in perimenopause and menopause are not character flaws, not the inevitable taxes of aging, and not problems you are supposed to quietly accept. They are physiological events with physiological solutions, and you deserve to have those solutions offered to you.

Dr. Casperson covers the full terrain: how hormones drive libido (and what happens when those hormones shift), the pelvic floor and why it matters beyond just "not leaking when you sneeze," genitourinary syndrome of menopause (GSM) and the vaginal and urinary changes that no one warned you were coming, and the research on testosterone for women — a topic that American medicine has been absurdly slow to take seriously.

Her "earn your pellet" philosophy is worth spending time on, even if you disagree with it at first. The argument is not that pellets are bad — it's that hormones work better when they're working with a body that has been prepared for them: sleep, strength training, stress management, nutrition. You cannot hormone your way out of a lifestyle that is fighting against you. This is not a moral judgment. It is physiology.

What I kept thinking while reading this book is: why did I have to find this myself? Why did none of my doctors think to bring up any of this proactively? The answer, as Dr. Casperson makes clear, is partly training gaps and partly cultural discomfort with women's sexuality in general. Medicine never exactly rushed to study what happens to women's desire after fifty.

This book is the conversation your doctor should have started with you and didn't. Read it, and then maybe hand it to your doctor.

No one told me that perimenopause could crater my libido, make sex painful, and leave me feeling completely disconnected from my own body. My doctor certainly didn't bring it up. I had to piece it together myself — which is why books like this one matter so much.

Dr. Kelly Casperson is a urologist with a podcast and a very clear mission: to convince women that the sexual and physical changes of midlife are not their fault, not inevitable, and not things they have to just live with. She is warm, funny, direct, and appropriately outraged at how systematically undertreated women's sexual health is.

The book covers libido and the hormones that drive it, genitourinary syndrome of menopause (the vaginal and urinary changes nobody warned you about), pelvic floor health, and testosterone for women — a subject that American medicine has been embarrassingly slow to take seriously. She also explains her "earn your pellet" philosophy: hormones work better when your lifestyle is supporting them, not fighting them. This is not a lecture; it's practical and compassionate.

What stayed with me is the title itself. You are not broken. The things happening to your body have names, have mechanisms, and have treatments. You just need a doctor willing to have the conversation.

Dr. Casperson is that doctor. This book is that conversation.

⭐⭐⭐⭐⭐
Book 4
The Menopause Manifesto
Jennifer Gunter, MD (2021)

The OB/GYN Who Refuses to Let You Get Away With Anything — Including the Wellness Industry

I want to be honest with you about why I love this book, because it requires a small amount of nuance that I think is worth having.

Dr. Jennifer Gunter is not on the same page as Dr. Haver or Dr. Casperson on every HRT question. She is more conservative on some hormonal interventions. She is more skeptical of some of the anti-WHI arguments that other menopause advocates make passionately. If you've spent time in menopause Twitter or Instagram, you may have seen her clash with other experts in this space. I am not going to adjudicate those arguments here.

What I will tell you is this: The Menopause Manifesto is one of the most useful books in the genre, precisely because of the qualities that sometimes frustrate other menopause advocates — her willingness to question, to demand evidence, to refuse to let a compelling narrative substitute for data.

She is extraordinary on symptoms. The breadth of coverage here is remarkable: hot flashes, sleep disruption, joint pain, brain fog, mood changes, skin changes, genitourinary symptoms, cardiovascular changes, bone density, sexual health. She explains the biology of each symptom clearly enough that you understand what is actually happening to your body, not just what it feels like from the inside.

She is also devastating on the wellness industry. If you have spent money on any supplement marketed for menopause symptom relief — and I have, and most of us have — her chapter on that topic will sting a little. She does not let the supplement world off the hook the way other health writers sometimes do, and she is right not to.

The HRT coverage, I'll be direct, is less enthusiastic than what you'll find in Haver or Casperson. If you're looking for an evidence-based case for hormonal therapy, go read Estrogen Matters first, then come back to Gunter for the fuller picture. These books do not contradict each other so much as they calibrate differently — and having both perspectives makes you a sharper advocate for your own care.

Dr. Gunter's Substack, "The Vajenda," has 128,000 subscribers for a reason. She is one of the most important voices in women's health. Read this manifesto.

I want to recommend this book honestly, which means acknowledging upfront that Dr. Gunter is somewhat more conservative on HRT than other menopause advocates I follow and admire. If you want the full-throated case for hormone therapy, read Estrogen Matters by Bluming and Tavris. Then come back to this one for balance — because balance, in Dr. Gunter's hands, is genuinely illuminating.

What makes The Menopause Manifesto exceptional is the breadth and rigor of its symptom coverage, and its willingness to call out the wellness industry with real force. She covers the biology of hot flashes, sleep disruption, joint pain, brain fog, mood changes, skin changes, genitourinary symptoms, cardiovascular health, and bone density — all clearly, all with the sources to back it up. And then she goes after the supplement marketers who have built an entire industry on women's desperation for relief.

She is also one of the few menopause authors who writes with genuine anger on behalf of women, not a polished, PR-managed version of advocacy. The title word — manifesto — is not an accident.

I don't agree with every position in this book. I suspect Dr. Gunter wouldn't want me to. That's part of what makes it valuable. Read it alongside Haver and Bluming, and you'll come out with a much sharper sense of where the consensus lies and where the debates are genuinely live.

⭐⭐⭐⭐⭐
Book 5
How to Menopause
Tamsen Fadal (2024)

What Happens When a Patient Gets Fed Up and Becomes the Advocate She Needed

I am not a doctor. I want to say that at the top of every piece I write, because I think it matters — and because I think there is a kind of knowledge that comes from being the patient that doctors sometimes struggle to access from the outside, no matter how good they are.

Tamsen Fadal is not a doctor either. She was a local television news anchor who went through a perimenopause crisis — symptoms she didn't recognize, appointments that didn't help, the particular disorientation of feeling like your own body has become unfamiliar — and came out the other side as one of the most effective menopause advocates in the country. Her documentary The M Factor has reached hundreds of thousands of people. And now there is this book.

How to Menopause is not a clinical manual. Dr. Haver's book is the clinical manual; this is something different. This is a guide to the lived experience — the emotional disorientation of realizing something significant is happening to you, the frustration of medical encounters that go nowhere, the process of building a support system and a care team and a relationship with your own body that actually works.

What Tamsen does exceptionally well is the lifestyle architecture: the practical daily and weekly habits that support hormonal health whether or not you're on HRT. Sleep hygiene in the context of menopause — not generic sleep advice, but specific strategies for the specific things menopause does to your sleep. Exercise framing that doesn't make you feel guilty for not running marathons. Nutrition that is realistic for actual humans. The community piece — finding other women going through this, talking about it, refusing the isolation that the culture has historically demanded.

She is also exceptionally good on the emotional journey. The identity shift of midlife. The "is this just me?" question that so many women carry alone because we were never taught to talk about this. The process of becoming someone who knows what she needs and asks for it. That is not soft content. That is genuinely difficult, and she writes about it with both honesty and grace.

As a fellow non-doctor doing advocacy in this space, I feel something close to kinship with this book. We are both people who had to find the information ourselves, who were frustrated at having to work so hard for it, and who decided to make it easier for the next woman coming through. That impulse is one of the most powerful things about the menopause conversation happening right now.

I am not a doctor. Neither is Tamsen Fadal. That is one of the reasons I love this book.

She was a TV news anchor who went through a perimenopause crisis — the disorientation, the unrecognized symptoms, the medical appointments that went nowhere — and came out the other side an advocate. This book is the guide she wished she'd had.

It is not a clinical manual. For that, go read Mary Claire Haver. This is something different: a guide to the lived experience of menopause, the emotional journey, and the practical daily habits that support your health whether or not you're on HRT. She is especially good on sleep (specific strategies for menopause-specific disruption), on building community (the isolation of going through this alone is real and fixable), and on the identity shift that midlife brings — the process of becoming someone who knows what she needs and asks for it.

What I kept thinking while reading this: the women who need clinical information will find clinical information. But a lot of us also just need someone to say, "I know. It happened to me too. Here is what helped." Tamsen says that — with warmth, with specificity, and without ever condescending to the reader.

If you are feeling lost in perimenopause and the medical books feel overwhelming, start here. Then go read Haver.

⭐⭐⭐⭐⭐
Book 6
Next Level
Stacy Sims, PhD (2022)

The Exercise Scientist Who Finally Explained Why What I Was Doing Wasn't Working

Here is a thing that nobody told me when I was in my late thirties and starting to train harder because I could feel my body changing: the exercise science I was applying was largely built on research done on men. Not deliberately malicious — just the way research got done for decades. Young male subjects are easy to standardize. Women cycle. Women are harder to study. So the field studied men and assumed the findings transferred.

They do not transfer. Not uniformly. Not for women in perimenopause and menopause.

Dr. Stacy Sims is an exercise physiologist and researcher who has spent her career studying how exercise affects women specifically. Next Level is the book she wrote for women over forty — perimenopausal, menopausal, postmenopausal — and it is one of the most practically transformative books on this list because it changes not just what you know but what you do.

The central argument is this: women in midlife need to train differently, not just more. The long-duration moderate-intensity cardio that gets marketed as the safe, healthy exercise prescription is not actually optimal for women in this hormonal phase. What is optimal is heavier resistance training (heavier than most women are doing), high-intensity interval training at genuinely high intensities, adequate protein — substantially more than most women eat — and a training structure that stops treating women as people who simply need a smaller version of the men's program.

She covers VO2 max and why it predicts longevity in ways that most people don't understand until someone puts the data in front of them. She covers bone density — the training stimulus that actually builds bone, versus the training that feels good but doesn't do much. She covers protein requirements that are probably double what you're currently eating if you're following conventional nutrition guidance. She covers recovery and how hormonal shifts affect it.

I changed the way I train after reading this book. That is the highest compliment I can give a fitness book.

This book changed the way I exercise. That is the highest compliment I can give it.

Dr. Stacy Sims is an exercise physiologist who has spent her career doing what almost no one else was doing: studying how exercise affects women, specifically, rather than applying male-subject research to female bodies and hoping it works. In Next Level she applies that research to perimenopausal and postmenopausal women specifically, and the result is a complete re-orientation of what "healthy exercise" should look like for us.

The short version: you need to lift heavier than you think. You need to do HIIT at genuinely high intensities, not "hard-ish" intensities. You need substantially more protein than conventional nutrition guidance suggests. And the long-duration moderate-intensity cardio that gets sold as the safe, sensible exercise prescription is not actually doing what you think it's doing for women in this hormonal phase.

She also covers VO2 max and why it is one of the best predictors of longevity (and how to improve it), bone density and the specific training stimulus that actually builds bone, and recovery — how our hormonal changes affect how we bounce back and what to do about it.

The chapter on protein requirements alone was worth the price of the book. The chapter on why women need to lift heavy was the reason I went and restructured my entire training program.

Read this book. Then go lift something heavy.

⭐⭐⭐⭐⭐
Book 7
The Menopause Brain
Lisa Mosconi, PhD (2024)

The Book I Didn't Know I Was Waiting For — And Couldn't Stop Crying While Reading

I carry two copies of the APOE4 gene — one from each parent. That means I have significantly elevated lifetime risk for Alzheimer's disease. My mother has Alzheimer's. I have watched what that disease does to a person, to a family, to a life, and I do not intend to accept that fate without doing everything the evidence supports to reduce my risk.

When I heard that Lisa Mosconi — a neuroscientist at Weill Cornell who runs the Women's Brain Initiative and has been studying estrogen and brain health for over twenty years — had written a book specifically about menopause, the brain, and Alzheimer's risk, I started reading it before the pre-order even shipped.

The Menopause Brain is the most important book on this list for me personally. And I suspect it will be the most important book on this list for any woman who has Alzheimer's in her family, any woman who is APOE4-positive, any woman who has ever found herself standing in a room forgetting why she walked in and wondering whether this is just stress or whether it is the beginning of something she should be afraid of.

Here is what Dr. Mosconi establishes with imaging data, longitudinal research, and decades of clinical observation: the female brain undergoes a significant neurological transition during menopause, driven by the loss of estrogen — a molecule the brain is not designed to live without. The hippocampus (memory) and the default mode network (the brain's resting state, heavily implicated in Alzheimer's) are both estrogen-sensitive. When estrogen drops, these systems register the change in measurable ways.

The timing hypothesis — the idea that there is a neuroprotective window during which estrogen therapy reduces Alzheimer's risk, and that this window closes — is not speculation. It is supported by neuroimaging, epidemiological data, and molecular research. Dr. Mosconi does not overstate what we know. She is careful, qualified, scientifically precise. But what we know is already significant, and what we know is that time matters.

My mother went into menopause in the 1990s. She was never given HRT. Her Alzheimer's diagnosis came years later. I will never know whether hormone therapy would have changed her story. That question will live in me for the rest of my life.

What I can do — what I am doing — is make sure I have the information she was denied.

Read this book. Especially if you have APOE4. Especially if you have a mother with Alzheimer's. Especially if you have ever wanted to understand why the hormonal transition of menopause is not just a quality-of-life issue but a brain health event that deserves to be taken seriously.

I am APOE4/4 — two copies of the highest genetic risk factor for Alzheimer's disease. My mother has Alzheimer's. When Lisa Mosconi, one of the world's leading researchers on the female brain and Alzheimer's risk, published this book, I read it in two sittings and cried through parts of it.

The Menopause Brain establishes, with imaging data and two decades of research, something that medicine has been slow to acknowledge: the female brain undergoes a significant neurological transition during menopause, driven by estrogen loss. The hippocampus and other memory-critical regions are estrogen-sensitive. When estrogen drops, those systems register the change in measurable, visible ways.

The timing hypothesis — that there is a neuroprotective window for estrogen therapy, and that window closes — is not speculation. Dr. Mosconi presents the neuroimaging, the epidemiology, and the molecular biology. She is careful and precise about what we know versus what we suspect. But what we know is already significant enough that every woman approaching menopause deserves to have this information.

My mother was never given HRT. She was part of a generation of women who weren't, because the medical establishment took the option off the table in 2002 and didn't put it back. Whether HRT would have protected her memory, I will never know.

But I am going to make sure I have the information she was denied.

If you have Alzheimer's in your family, if you are APOE4-positive, or if you have ever wondered whether the brain fog of perimenopause is telling you something important — read this book.

⭐⭐⭐⭐⭐
Book 8
Outlive: The Science and Art of Longevity
Peter Attia, MD (2023)

The Longevity Playbook That Belongs on Every Midlife Woman's Shelf — Even Though She Is Not His Primary Audience

I want to be honest about something: Outlive was not written primarily for perimenopausal women. It was written by a physician who is primarily treating high-performing men who want to live to a hundred without falling apart. The book reflects that lens in places — and there are moments when the hormonal health chapter reads like something that was added because it had to be included, rather than something Dr. Attia has spent his career on.

With that caveat firmly in place: this book should be on your shelf anyway.

Here is why. Dr. Attia's contribution is a reframing of what medicine is even for — what he calls "Medicine 3.0" versus the reactive, disease-management model most of us have experienced. His argument is that the four chronic diseases most likely to kill us (cardiovascular disease, cancer, metabolic dysfunction, and neurological decline, including Alzheimer's) all have substantial behavioral and physiological precursors that begin decades before diagnosis. Medicine 3.0 starts intervening at the precursor stage, not the emergency stage. That framing changes everything about how you think about the choices you're making in your forties and fifties.

The cardiovascular health chapter is exceptional. The metabolic health coverage — insulin resistance, blood glucose variability, what continuous glucose monitoring actually tells you — is some of the best lay-reader explanation I have found anywhere. The strength and VO2 max chapters should be read alongside Stacy Sims for the female-specific layer, but Attia's data on why these two metrics predict longevity more than almost anything else we can measure is stark and compelling. The section on zone 2 training — low-intensity aerobic work at a specific heart rate range — is the piece I quote most often.

The HRT chapter is good but not great — Dr. Attia is broadly supportive of hormone therapy for women where indicated, which is important given his stature in longevity medicine, but he does not go as deep as Bluming or Haver. Read it for the endorsement; read those books for the evidence.

What Outlive gives you, more than any other book on this list, is a framework for asking the right questions. What should I be optimizing for at fifty? Which numbers actually predict long-term health versus which ones are just what the current healthcare system happens to test for? What does it look like to train toward being a capable, independent, strong eighty-year-old — and what do you have to do now to get there?

SmartStrongAlive is built on this framing. This is the book that articulates it most rigorously.

This was not written for women in perimenopause. I want to be honest about that. Peter Attia's primary patient population skews male and high-performing, and the book reflects that in places.

But read it anyway.

Because what Outlive provides — above and beyond any specific recommendations about HRT or hormones — is a framework that completely reorients how you think about your health in midlife. Medicine 3.0, as he calls it, is not about treating disease when it arrives. It's about understanding the decades-long precursors to cardiovascular disease, metabolic dysfunction, cancer, and neurological decline — and intervening early, when the interventions actually work.

The cardiovascular chapter is exceptional. The metabolic health section — insulin resistance, glucose variability, what your labs actually mean — is the best lay-reader explanation I've found. The data on VO2 max and strength as predictors of longevity is sobering and motivating in equal measure. The zone 2 training chapter changed how I think about my weekly exercise.

Read this alongside Stacy Sims (Next Level) for the female-specific layer on exercise, and alongside Bluming and Haver for the HRT evidence that Attia covers more lightly than the specialists do.

The HRT chapter is supportive without being comprehensive — which is honestly enough. Having a physician of Attia's credibility in longevity medicine say clearly that hormone therapy should be considered rather than avoided is meaningful.

This is one of the most important books written on health in the last decade. Worth every hour.

⭐⭐⭐⭐⭐
Book 9
Preparing for the Perimenopause and Menopause
Louise Newson, MD (2021)

The British Doctor Who Sent Me Down a Path That Changed Everything

I want to tell you something personal about this book.

I was a patient at Newson Health. I went to Louise Newson's clinic — not because I lived in the UK, but because I had tried the options available to me in the US and I still did not feel right. And at Newson Health, for the first time, I was seen by a doctor who treated the menopause conversation not as a risk management exercise to get through as quickly as possible, but as a serious clinical evaluation of what my specific body needed. I came home with a care plan that included AndroFeme — the testosterone cream Dr. Newson's clinic prescribes, and which I could not easily have gotten anywhere else.

Dr. Newson is the UK's most prominent menopause specialist. She founded Newson Health, which has transformed how perimenopause and menopause are managed in Britain. She has testified before Parliament. She has trained thousands of GPs. She has built an evidence-based clinical approach to hormonal health that, frankly, puts most US practice to shame in terms of breadth and individualization.

This book is the accessible, reader-facing version of her clinical philosophy. It is practical in the best sense — structured around what women actually need to understand to advocate for themselves — and it is quietly devastating about the state of menopause care globally.

The UK and the US have different healthcare landscapes, and some of the specific guidance in this book reflects UK prescribing conventions. In Britain, transdermal estrogen and progesterone are more commonly prescribed than oral forms; testosterone for women is more normalized; GPs are more likely to have received menopause-specific training than their American counterparts. These differences matter, and American readers should read with that context in mind.

But the core of this book — the case for taking perimenopause symptoms seriously, the evidence for HRT, the argument that women's hormonal health is a long-term investment in cardiovascular, bone, and brain health, not a short-term symptom fix — translates perfectly. Dr. Newson makes the case with the precision of a clinician and the urgency of someone who has watched too many patients suffer unnecessarily.

I trust this woman with my hormonal health. I trust this book to give you the foundation to start advocating for yours.

I am not an impartial reader of this book. I was a patient at Newson Health — I flew to the UK to see a doctor who would actually take my hormonal health seriously after years of feeling dismissed and undertreated at home. Dr. Newson's clinic gave me a care plan that included AndroFeme (the testosterone cream her clinic prescribes) and a level of individualized clinical attention I could not find in the US.

So yes, I am biased. I think she is exceptional.

This book is the accessible version of her clinical philosophy, and it is exactly what it claims to be: a preparation guide for perimenopause and menopause that treats the reader as an intelligent adult who deserves real information.

She covers symptoms, HRT options, the evidence for long-term hormonal health benefits (cardiovascular, bone, brain), and the practical questions of how to find a doctor who will take you seriously. American readers should know that some prescribing conventions differ between the UK and US — transdermal estrogen and testosterone for women are more normalized in Britain than in most American practices — but the core clinical arguments translate completely.

The section that stayed with me is her discussion of what happens to women who go without HRT when they need it — the long-term consequences for bone density, cardiovascular health, and cognitive function that nobody warned them about. She does not sensationalize it. She just tells you the truth.

For anyone who wants to understand perimenopause from the perspective of a doctor who has made it her life's work: this is the book.

⭐⭐⭐⭐⭐
Book 10
The Menopause Moment
Kelly Casperson, MD (2025)

She Already Told You That You're Not Broken. Now She's Telling You What to Build.

There is a specific kind of dread that lives in my body when I think about what happened to my mother. She went into menopause in the mid-1990s. By 2002, when the Women's Health Initiative made headlines, her doctors had already quietly stopped offering hormone therapy. She aged into her sixties without any hormonal support, without any conversation about what estrogen actually does in the brain, and today she has Alzheimer's. I do not know whether HRT would have changed her story. Nobody does. What I know is that she was never given the chance to find out, because medicine decided the question wasn't worth asking.

I carry the APOE4 gene. I have watched what Alzheimer's does to a family from the inside. So when I read a book that frames menopause not as a symptom management problem but as a longevity decision point, I am not reading it as an interested observer. I am reading it as someone who has a lot at stake and very little patience for anything that softens the urgency.

Dr. Kelly Casperson earned my trust with her first book. You Are Not Broken was about sexual health and the radical, well-documented claim that women's midlife symptoms have been systematically dismissed. That book told you to stop apologizing. It was the permission slip. The Menopause Moment is the blueprint.

The piece that stopped me cold was her treatment of mindset as a clinical variable. I went in expecting this to be the soft-skills chapter I could skim on my way to the hormone protocols. I came out having taken notes. The nocebo effect is not a psychological curiosity. Negative expectation about what menopause will do to you activates the hypothalamic-pituitary-adrenal axis, raises cortisol chronically, suppresses immune function, and amplifies pain signaling. Your dread of decline has a physiology. Dr. Casperson is not telling you to think positive thoughts. She is telling you that the story you carry into this transition shapes what is biologically possible inside it. "Decline" is not a neutral word. She would like you to retire it.

The longevity framing is where this book earns its subtitle. Estrogen is not a hot-flash drug. It is a molecule with receptors in cardiac muscle, vascular endothelium, bone, neurons, and skeletal muscle. When those receptors go unfilled for decades, the consequences accumulate in ways that are harder to see than a hot flash but far more consequential: arterial stiffening, bone resorption that outpaces formation, impaired amyloid clearance in the brain, reduced synaptic density in the hippocampus. Dr. Casperson makes the case for hormonal support as a long-term investment in cardiovascular, skeletal, and cognitive health, not a short-term symptom fix. This is not a new argument. What she does is make it accessible, urgent, and personal.

The timing window is the part that matters most to me. There is a period surrounding menopause onset during which estrogen therapy has a meaningful neuroprotective effect, and a point past which those protections are no longer available in the same way. Women who wait until their symptoms become undeniable, or until a doctor finally takes them seriously, may have already moved past the window during which the intervention does its most important work. As an APOE4 carrier, that is not an abstraction. The evidence linking early hormone therapy to reduced Alzheimer's risk in women with my genotype is among the most compelling data I have encountered in all of this reading. Casperson does not overstate it. She does not soften it either.

Read You Are Not Broken first, if you haven't. That book gives you the permission. This one gives you the plan. Together they are the most complete picture of what it looks like when a doctor takes women's midlife health seriously, and when you decide to take it seriously alongside her. I read this one with a highlighter and a low-grade grief for my mother and a very clear sense of my own urgency. That is exactly what it is supposed to do.

I already trusted Kelly Casperson before I opened this book. You Are Not Broken was the first book that made me feel like a doctor was genuinely on my side in the menopause conversation, not managing my expectations or rushing toward the door. So when she came back with a second book, I picked it up wanting to know where she was taking this next.

What she delivers is the natural evolution of the first book. Less "you're not broken" and more "here is what optimal actually looks like." The frame is longevity: hormones not as symptom management but as long-term investments in cardiovascular health, bone density, and cognitive protection. She is direct about the timing window, about what happens biologically when women wait too long to initiate hormonal support, and about why the goal is not to survive menopause but to build the physiological foundation for the next thirty years.

The part that stayed with me is her argument that mindset is a clinical variable, not a soft add-on. How you frame this transition shapes what is biologically possible inside it. The nocebo effect is real, it has a mechanism, and it matters. She backs that up with actual science, and it made me rethink the vocabulary I have been using to describe this period in my own life.

As someone who carries the APOE4 gene and has watched my mother move through Alzheimer's, the cognitive protection sections landed differently for me than they might for someone with a lower-stakes reason to read. The timing window is not an abstraction when cognitive decline is something you are actively trying to prevent. Casperson does not soften that urgency, and I am grateful she doesn't.

Read You Are Not Broken first if you haven't. Then read this one. Together they are the conversation your doctor should have started with you years ago.

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